The Danger Theory: Twenty Years Later

The Danger Theory: Twenty Years Later

Blog Article

The self-nonself theory has dominated immunology since the 1950s.In the Sharps Collectors - Brackets and Cabinets 1990s, Matzinger and her colleagues suggested a new, competing theory, called the danger theory.This theory has provoked mixed acclaim: enthusiasm and criticism.

Here we assess the danger theory vis-à-vis recent experimental Fluids data on innate immunity, transplantation, cancers and tolerance to foreign entities, and try to elucidate more clearly whether danger is well defined.